Macular Thickness Profile and Its Association With Best-Corrected Visual Acuity in Healthy Young Adults

Purpose: To describe the thickness profiles of full retinal and outer layers (ORL) at macula in healthy young adults, associations with best-corrected visual acuity (BCVA). Methods: In total, 1604 participants (19-30 years) underwent an eye examination that included measurements their BCVA, axial length, autorefraction. The foveal pit nine Early Treatment Diabetic Retinopathy Study macular regions (0.5-mm radius around fovea, superior, inferior, temporal, nasal quadrants inner rings macula) were obtained using spectral-domain optical coherence tomography imaging. A custom program was used to correct for transverse magnification effects because different lengths. Results: median ORL thicknesses central 285 µm 92 µm. retina thinnest centrally thickest ring, whereas gradually decreased increasing eccentricity. There no association between length or thickness. Increased associated better BCVA; however, effect size small not clinically significant. Conclusions: This article mapped profile a population-based sample adults. Translational relevance: Thickness values presented this could be as normative reference future studies on adults clinical practice.